Medical awareness of CF has increased tremendously over the years. Nevertheless, cystic fibrosis can still be confused with other common diseases -- such as asthma, chronic bronchitis or pneumonia, and celiac disease.

Cystic Fibrosis was first described as a disease in the late 1930s. At that time, it was usually recognized only after a child had died, often as a result of malnutrition or pneumonia.

SYMPTOMS OF CYSTIC FIBROSIS

• difficulty breathing
• constant cough which expels thick mucus
• excessive appetite, with weight loss
• bowel disturbances
• skin which tastes salty
• repeated or prolonged bouts of pneumonia
• failure to thrive

WHAT CAUSES CYSTIC FIBROSIS?

People are born with cystic fibrosis; it is a genetic disorder.

Approximately one in every 25 Canadians carries a defective version of the gene responsible for CF. A carrier has only one copy of the gene responsible for CF. Carriers do not have cystic fibrosis, and can never get the disease. In most cases, they are not even aware that they are carriers, because they do not have cystic fibrosis, or any of its symptoms.

When two people who carry a defective version of the gene responsible for CF have a child, there is:

• a 25% chance that the child will be born with cystic fibrosis
• a 50% chance that the child will not have CF, but will be a carrier
• a 25% chance that the child will not have CF, and will not be a carrier

With each pregnancy, the risks are exactly the same. Two carrier parents may have several children with CF or none at all.

DIAGNOSIS OF CYSTIC FIBROSIS

If a physician suspects CF, he or she will probably suggest a "sweat test". This simple and painless test measures the amount of salt in the sweat. A high salt level, along with other symptoms, points to the presence of cystic fibrosis.

Increasingly, genetic tests are being used in the diagnosis of the disease. Genetic tests are also used to diagnose CF prenatally.

When is cystic fibrosis diagnosed?
Approximately 60% of patients are diagnosed in the first year of life, and 90% by 10 years of age.